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Cholesterol buildup in brain presents new target to reduce dementia risk from stroke
University of Arizona Health Sciences researchers suggest the risk of developing dementia after a stroke might be reduced by a drug that could help immune cells process the cholesterol-rich debris generated by a stroke. Today University of Arizona Health SciencesHealthBIO5College of Medicine - TucsonCollege of PharmacyExploration Media contact(s)Anna Christensen University of Arizona Health Sciencesachristensen@arizona.edu520-626-7383University of Arizona Health Sciences researchers discovered a potential treatment to reduce the risk of post-stroke dementia, which may be influenced by the immune response to dead bra...
Source: The University of Arizona: Health - January 19, 2022 Category: Universities & Medical Training Authors: mittank Source Type: research

UCLA brain-imaging tool and stroke risk test help identify cognitive decline early
UCLA researchers have used a brain-imaging tool and stroke risk assessment to identify signs of cognitive decline early on in individuals who don't yet show symptoms of dementia.   The connection between stroke risk and cognitive decline has been well established by previous research. Individuals with higher stroke risk, as measured by factors like high blood pressure, have traditionally performed worse on tests of memory, attention and abstract reasoning.   The current small study demonstrated that not only stroke risk, but also the burden of plaques and tangles, as measured by a UCLA brain scan, may influence c...
Source: UCLA Newsroom: Health Sciences - April 3, 2013 Category: Universities & Medical Training Source Type: news

Importance of Retesting for the Final Diagnosis of Post-Stroke Cognitive Impairment
Conclusions: We established the prevalence of CogI and its course after 6 months in a well-defined group of patients after a mild ischaemic stroke (mean NIHSS: 2 and mean mRS: 1 at the discharge). Our results show that the prevalence of CogI after an ischaemic stroke at discharge is relatively high (74%), and it tends to be a spontaneous reduction. Cognitive functions were changed in 35% of patients. The definition of PSCI was completed in only 24% of individuals. Only an examination several months after a stroke can give us more accurate information about the true prevalence of persistent CogI after a stroke.PMID:36984638...
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Dominik Koren Miriam Slavkovska Marianna Vitkova Zuzana Gdovinova Source Type: research

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