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Historical Perspective: A "Quick" Narrative of a Blood Coagulation Trailblazer
Physicians know Dr Armand Quick as the "Father of Blood Coagulation." His discovery of prothrombin time enabled clinicians to understand the use of vitamin K to prevent "hemorrhagic disease of the newborn" and to identify hereditary and acquired bleeding disorders in pediatric and adult patients. Quick suggested 50 years ago that aspirin could prevent myocardial infarction and stroke, a concept that perseveres today. His lifetime of research on bleeding and anticoagulants created this discipline in modern hematology.
Source: NeoReviews recent issues - October 31, 2016 Category: Pediatrics Authors: Wahidi, L. S., Sherman, J., Sherman, M. P. Tags: Pediatric Drug Labeling Update Articles Source Type: news

Warfarin Use May Not Bring Long-Term Stability for Atrial Fibrillation
Contact: Amara Omeokwe Phone: 919-681-4239 Email:amara.omeokwe@duke.eduhttps://www.dukehealth.orgEMBARGOED FOR RELEASE until 11 a.m. (ET) on Tuesday, Aug. 9, 2016DURHAM, N.C. -- Warfarin prescribed to prevent strokes in atrial fibrillation may not adequately control blood clotting over the long-term, even when patients have been historically stable on the drug, according to a study from the Duke Clinical Research Institute.The findings, published Aug. 9 in the Journal of the American Medical Association (JAMA), are based on an 18-month study of 3,749 patients diagnosed with atrial fibrillation, an irregular heart rhythm. T...
Source: DukeHealth.org: Duke Health Features - August 9, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

What Are Common Inherited Thrombophilias?
Discussion Thrombophilia is the increased risk of thromboembolic disease due to a disorder. Thrombophilia can be inherited or acquired (such as antiphospholipid syndrome). The risk of thromboembolic events is much lower in children than adults. At-risk patients should avoid: Dehydration Sitting for prolonged time periods during travel Obesity Smoking Estrogen containing oral contraceptives Common inherited thrombophilias include: Prothrombin (Factor II mutation) Second most common Genetics: 1-2% prevalence is variable depending on location and ethnic background. Cause: Abnormal point mutation of the prothrombin gene t...
Source: PediatricEducation.org - May 25, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news