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Effect of frailty on major bleeding in octogenarian patients undergoing percutaneous coronary intervention
CONCLUSIONS: Frailty is an independent predictor of major bleeding in patients undergoing PCI for acute coronary syndrome. Use of the P2Y12 inhibitor ticagrelor increases the risk of major bleeding in frail patients.PMID:37318490 | DOI:10.26355/eurrev_202306_32633
Source: European Review for Medical and Pharmacological Sciences - June 15, 2023 Category: Drugs & Pharmacology Authors: K Özbek A Balun Source Type: research

Middle East Treatment Strategies and Clinical Outcomes in Patients with Atrial Fibrillation: One-Year Follow-up Data from Garfield-AF Study
ConclusionWe have found that rates of stroke and bleeding were lower, although mortality was higher, in the Middle East population. This paper describes the baseline characteristics, patterns of antithrombotic treatment and 1-year outcomes in Middle East AF patients.Trial Registrationhttp://www.clinicaltrials.gov. Identifier, NCT01090362.
Source: Advances in Therapy - March 27, 2021 Category: Drugs & Pharmacology Source Type: research

The harm of anticoagulation in patients with low-risk by CHADS2 and reclassified as high-risk by CHA2DS2VASc: inferences from TRAF cohort.
CONCLUSIONS: Clinical outcomes, net clinical benefit indices are negative; rates of death and hospitalization were significantly higher for OAC in reclassified category. This emphasizes the importance of greater attention to balancing the risks and benefits of OAC in patients with low risk by CHADS2 and reclassified as high-risk by CHA2DS2VASc. PMID: 33215439 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - November 22, 2020 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Cost analysis of management of cardiovascular disease comorbidities in Turkey
ConclusionThe study findings helped gain an insight into the most prominent comorbidities associated with CVDs in the perspective of reimbursement institution including direct costs. Further studies are needed to understand the real cost for reimbursement institution.
Source: Journal of Pharmaceutical Health Services Research - May 15, 2019 Category: Drugs & Pharmacology Authors: G üvenç Koçkaya, Gülpembe Ergin Oğuzhan, Bülent Özin, Kerem Can Yılmaz, Orçun Çiftçi, Filiz Çavuş, Amir Mustapha Sharaf, Nazım Buyuktuna, Tansu Buyukısık, Mete Saylan Tags: Research Paper Source Type: research