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Concomitant Use of NSAIDs or SSRIs with NOACs Requires Monitoring for Bleeding.
CONCLUSION: When NSAIDs or SSRIs are required for NOAC users with AF, physicians need to monitor bleeding events and consider the use of PPIs, especially for combined use of both drugs or when initiating NOACs treatment. PMID: 32882758 [PubMed - in process]
Source: Yonsei Medical Journal - August 31, 2020 Category: Universities & Medical Training Authors: Lee MT, Park KY, Kim MS, You SH, Kang YJ, Jung SY Tags: Yonsei Med J Source Type: research

Evaluating Effectiveness and Safety in Chronic Kidney Disease with Atrial Flutter Using an Anticoagulation Strategy.
Conclusions: In the studied population, OAC or APT alone were proved equally effective for stroke prophylaxis. Furthermore, OAC might reduce the all-cause mortality rate compared with APT and should be considered as the first choice of oral antithrombotic drugs in patients with AFL and CKD. PMID: 32481685 [PubMed - in process]
Source: Medicina (Kaunas) - May 27, 2020 Category: Universities & Medical Training Authors: Wang YT, Chen CY, Bair MJ Tags: Medicina (Kaunas) Source Type: research

Antithrombotic Medication and the Risk of Vitreous Hemorrhage in Atrial Fibrillation: Korean National Health Insurance Service National Cohort.
CONCLUSION: Dual antiplatelet or triple therapy increased the risk of VH significantly, compared to warfarin monotherapy. Considering the low efficacy of preventing ischemic stroke and high risk of bleeding, dual or triple therapy using warfarin and antiplatelet agents should be avoided to prevent VH in AF patients. PMID: 30554492 [PubMed - in process]
Source: Yonsei Medical Journal - December 18, 2018 Category: Universities & Medical Training Authors: Kim KE, Yang PS, Jang E, Kim S, Joung B Tags: Yonsei Med J Source Type: research