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New Biomarkers for Atherothrombosis in Antiphospholipid Syndrome: Genomics and Epigenetics Approaches
Conclusions In recent years, there have been many advances in the understanding of the molecular basis for vascular involvement in APS, but many areas need to be further investigated, in particular the association between altered genetic/epigenetic profiles, autoantibodies and clinical manifestations, and the effectiveness of new therapeutic strategies. It would be interesting to apply next generation sequencing technologies like RNA-Seq along with GWAS to screen both, the gene profile and the whole transcriptome of large cohorts of primary APS patients, in order to reveal the mutations/polymorphisms, post-transcriptiona...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

Obesity Prevention Resources for Special Populations
From the NLM Outreach and Special Populations Branch: Obesity is a major health issue in the United States, and the Centers for Disease Control and Prevention (CDC) offer some alarming facts about obesity in both adults and children in the US: Obesity affects about 1 in 6 children in the US. More than 1/3 of US adults are obese. The highest age-adjusted rates of obesity impact African Americans (48.1%) followed by Hispanic Americans (42.5%). Obesity can put an individual at increased risk for diabetes, heart disease, stroke, arthritis, and some cancers. Changes in nutrition and exercise habits can help to prevent obes...
Source: NN/LM Middle Atlantic Region Blog - July 5, 2017 Category: Databases & Libraries Authors: Hannah Sinemus Tags: Consumer Health Education Public Health Source Type: news