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Source: Arthritis and Rheumatology
Condition: Arthritis

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Total 20 results found since Jan 2013.

Genetic liability to rheumatoid arthritis in relation to coronary artery disease and stroke risk
ConclusionThis study found that genetic liability to RA was associated with increased risk of CAD and intracerebral hemorrhage and that the association for CAD might be mediated by CRP. The heightened cardiovascular risk should be actively monitored and managed in RA patients, and this may include damping systemic inflammation.
Source: Arthritis and Rheumatology - May 18, 2022 Category: Rheumatology Authors: Shuai Yuan, Paul Carter, Amy M. Mason, Fangkun Yang, Stephen Burgess, Susanna C. Larsson Tags: Full Length Source Type: research

COVID ‐19 Outcomes in Patients With Systemic Autoimmune Rheumatic Diseases Compared to the General Population: A US Multicenter, Comparative Cohort Study
ConclusionOur findings indicate that COVID ‐19 patients with systemic ARDs may be at a higher risk of hospitalization, ICU admission, acute renal failure, and venous thromboembolism when compared to COVID‐19 patients without systemic ARDs. These risks may be largely mediated by comorbidities, except for the risk of venous thromboembolism .
Source: Arthritis and Rheumatology - May 1, 2021 Category: Rheumatology Authors: Kristin M. D ’Silva, April Jorge, Andrew Cohen, Natalie McCormick, Yuqing Zhang, Zachary S. Wallace, Hyon K. Choi Tags: Brief Report Source Type: research

Cardiovascular and Renal Morbidity in Takayasu Arteritis: A Population ‐Based Retrospective Cohort Study From the United Kingdom
ConclusionCardiovascular morbidity was increased among patients with TAK receiving primary care services in the UK. Treatment with statins and antiplatelet agents in these patients was suboptimal.
Source: Arthritis and Rheumatology - February 27, 2021 Category: Rheumatology Authors: Ruchika Goel, Joht Singh Chandan, Rasiah Thayakaran, Nicola J. Adderley, Krishnarajah Nirantharakumar, Lorraine Harper Tags: Full Length Source Type: research

COVID ‐19 Outcomes in Patients with Systemic Autoimmune Rheumatic Diseases (SARDs) Compared to the General Population: A US Multi‐Center Comparative Cohort Study
ConclusionsSARD patients with COVID ‐19 may be at higher risk of hospitalization, ICU admission, ARF, and VTE versus matched comparators. These risks may be largely mediated by comorbidities, except for risk of VTE.
Source: Arthritis and Rheumatology - December 10, 2020 Category: Rheumatology Authors: Kristin M. D ’Silva, April Jorge, Andrew Cohen, Natalie McCormick, Yuqing Zhang, Zachary S. Wallace, Hyon K. Choi Tags: BRIEF REPORT Source Type: research

Cardiovascular and renal morbidity in Takayasu arteritis: a population ‐based retrospective cohort study from UK
ConclusionCardiovascular morbidity was increased in patients with TA attending primary care services in the UK. Treatment with statins and anti ‐platelets in these patients was suboptimal.
Source: Arthritis and Rheumatology - September 22, 2020 Category: Rheumatology Authors: Ruchika Goel, Joht Singh Chandan, Rasiah Thayakaran, Nicola J Adderley, Krishnarajah Nirantharakumar, Lorraine Harper Tags: FULL LENGTH Source Type: research

Anti –Citrullinated Protein Antibody Specificities, Rheumatoid Factor Isotypes, and Incident Cardiovascular Events in Patients With Rheumatoid Arthritis
ConclusionRF isotypes and ACPAs are associated with future CV events in patients with RA. ACPA levels and number of subspecificities seem more important than the occurrence of particular subspecificities, and these associations were not explained by a history of ever smoking.
Source: Arthritis and Rheumatology - September 6, 2020 Category: Rheumatology Authors: Helga Westerlind, Johan R önnelid, Monika Hansson, Lars Alfredsson, Linda Mathsson‐Alm, Guy Serre, Martin Cornillet, Rikard Holmdahl, Per‐Johan Jakobsson, Karl Skriner, Lars Klareskog, Saedis Saevarsdottir, Johan Askling Tags: Original Article Source Type: research

Deficiency of adenosine deaminase 2 (DADA2) in Adults and Children: Experience from India
ConclusionsWe present the first case series of DADA2 patients from India. We highlight the presentation of DADA2 in adults and raise awareness of this syndrome for both adult and paediatric care providers.
Source: Arthritis and Rheumatology - September 5, 2020 Category: Rheumatology Authors: Aman Sharma, Gsrsnk Naidu, Vikas Sharma, Saket Jha, Aaadhar Dhooria, Varun Dhir, Prateek Bhatia, Vishal Sharma, Sagar Bhattad, Chengappa, Vikas Gupta, Durga Prasanna Misra, Pallavi Pimpale Chavan, Sourabh Malaviya, Rajkiran Dudam, Banwari Tags: FULL LENGTH Source Type: research

Biologics May Prevent Cardiovascular Events in Rheumatoid Arthritis by Inhibiting Coronary Plaque Formation and Stabilizing High ‐Risk Lesions
ConclusionOur findings indicate that in RA, biologic DMARD use is associated with reduced CVD risk, protective calcification of noncalcified lesions, and lower likelihood of new plaque formation in patients with early atherosclerosis.
Source: Arthritis and Rheumatology - August 6, 2020 Category: Rheumatology Authors: George A. Karpouzas, Sarah R. Ormseth, Elizabeth Hernandez, Matthew J. Budoff Tags: Original Article Source Type: research

Antiphospholipid Syndrome is still a rare disease: the estimated prevalence in Piedmont and Aosta Valley
AbstractWe read with interest the recent article by Duarte ‐García, A. et al. where they reported an estimated prevalence of the antiphospholipid syndrome (APS) of 50 cases per 100,000 population. APS is an autoimmune disorder characterized by thrombotic events, pregnancy morbidity, or both in the presence of persistent positivity for antiphospholipid an tibodies (aPL). While APS is often held as the most common acquired thrombophilia, the global incidence and the prevalence of APS in the general population still need to be fully elucidated. Some reports estimate an incidence of 5 cases per 100,000 persons per year and ...
Source: Arthritis and Rheumatology - June 16, 2020 Category: Rheumatology Authors: Massimo Radin, Savino Sciascia, Mario Bazzan, Tiziana Bertero, Renato Carignola, Barbara Montaruli, Antonella Vaccarino, Erika Montabone, Irene Cecchi, Elena Rubini, Dario Roccatello, Simone Baldovino, on behalf of the Piedmont, Aosta Valley APS Consortiu Tags: LETTER TO THE EDITOR Source Type: research

Anti ‐citrullinated protein antibody specificities, rheumatoid factor isotypes and incident cardiovascular events in patients with rheumatoid arthritis
ConclusionsRF isotypes and ACPA are associated with future CV events. ACPA levels and number of sub ‐specificities seem more important than the occurrence of particular sub‐specificities. These associations were not explained by smoking.
Source: Arthritis and Rheumatology - May 30, 2020 Category: Rheumatology Authors: Helga Westerlind, Johan R önnelid, Monika Hansson, Lars Alfredsson, Linda Mathsson‐Alm, Guy Serre, Martin Cornillet, Rikard Holmdahl, Per‐Johan Jakobsson, Karl Skriner, Lars Klareskog, Saedis Saevarsdottir, Johan Askling Tags: FULL LENGTH Source Type: research

Biologics may prevent cardiovascular events in rheumatoid arthritis by inhibiting coronary plaque formation and stabilizing high ‐risk lesions
ConclusionIn rheumatoid arthritis, bDMARD use associated with reduced CVD risk, protective calcification of non ‐calcified lesions and lower likelihood of new plaque formation in patients with early atherosclerosis.
Source: Arthritis and Rheumatology - April 20, 2020 Category: Rheumatology Authors: George A Karpouzas, Sarah R Ormseth, Elizabeth Hernandez, Matthew J Budoff Tags: FULL LENGTH Source Type: research

Role of Nonsteroidal Antiinflammatory Drugs in the Association Between Osteoarthritis and Cardiovascular Diseases: A Longitudinal Study
ConclusionThe findings of this first study to evaluate the mediating role of NSAIDs in the relationship between OA and CVD suggest that NSAID use contributes substantially to the OA –CVD association.
Source: Arthritis and Rheumatology - September 4, 2019 Category: Rheumatology Authors: Mohammad Atiquzzaman, Mohammad E. Karim, Jacek Kopec, Hubert Wong, Aslam H. Anis Tags: Original Article Source Type: research

Role of Non ‐Steroidal Anti‐Inflammatory Drugs (NSAIDs) in the Association between Osteoarthritis and Cardiovascular Diseases: A Longitudinal Study
ConclusionFindings of this first study to evaluate NSAID's mediating role in OA ‐CVD relationship suggest that NSAID use substantially contributes to the OA‐CVD association.This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - August 5, 2019 Category: Rheumatology Authors: Mohammad Atiquzzaman, Mohammad E. Karim, Jacek Kopec, Hubert Wong, Aslam H. Anis Tags: Full Length Source Type: research

A Multicenter, Randomized, Placebo ‐Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis
ConclusionAtorvastatin 40 mg daily is safe and results in a significantly greater reduction of LDL cholesterol level than placebo in patients with RA. The 34% CVE risk reduction is consistent with the Cholesterol Treatment Trialists ’ Collaboration meta‐analysis of statin effects in other populations.
Source: Arthritis and Rheumatology - July 21, 2019 Category: Rheumatology Authors: George D. Kitas, Peter Nightingale, Jane Armitage, Naveed Sattar, Jill J. F. Belch, Deborah P. M. Symmons, on behalf of the TRACE RA Consortium, George Kitas, Jill Belch, Deborah Symmons, Hawys Williams, Shobna Vasishta, Rebecca Storey, Pete Tags: Original Article Source Type: research

Identification of novel Adenosine Deaminase 2 gene variants and varied clinical phenotype in pediatric vasculitis
ConclusionOur findings support previous reports that DADA2 has extensive genotypic and phenotypic variability. We suggest that screeningADA2 among children with vasculitic rash, UCV, PAN, or unexplained early ‐onset CNS disease with systemic inflammation may enable an earlier diagnosis of DADA2.This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - April 21, 2019 Category: Rheumatology Authors: Kristen M Gibson, Kimberly A Morishita, Paul Dancey, Paul Moorehead, Britt Dr ögemöller, Xiaohua Han, Jinko Graham, Robert EW Hancock, Dirk Foell, Susanne Benseler, Rashid Luqmani, Rae S M Yeung, Susan Shenoi, Marek Bohm, Alan M Rosenberg, Tags: Full Length Source Type: research