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A Complicated Case of Haemophilus influenzae Endocarditis in an Adult
Bacterial causes for infective endocarditis have changed over the years, with Staphylococcus aureus now being the most common pathogen isolated. With the advent of routine childhood vaccinations, invasive infections caused by Haemophilus influenzae have become rare. We wish to report a case of infective endocarditis caused by H. influenzae that was complicated by meningitis, septic arthritis, and stroke.
Source: Infectious Diseases in Clinical Practice - April 24, 2020 Category: Infectious Diseases Tags: Case Reports Source Type: research

Investigating the candidacy of the serotype specific rhamnan polysaccharide based glycoconjugates to prevent disease caused by the dental pathogen Streptococcus mutans
AbstractDental caries remains a major health issue and the Gram-positive bacteriumStreptococcus mutans is considered as the major pathogen causing caries. More recently,S. mutans has been recognised as a cause of endocarditis, ulcerative colitis and fatty acid liver disease along with the likelihood of increased cerebral hemorrhage following a stroke ifS. mutans is present systemically. We initiated this study to examine the vaccine candidacy of the serotype specific polysaccharides elaborated byS. mutans. We have confirmed the carbohydrate structures for the serotype specific rhamnan containing polysaccharides from seroty...
Source: Glycoconjugate Journal - October 2, 2017 Category: Biochemistry Source Type: research