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Condition: Endocarditis
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Total 767 results found since Jan 2013.
A Puzzling Case of Cryptogenic Stroke
Background: Stroke is a common neurological complication of infective endocarditis (IE) and it is associated with increased morbidity and mortality but infective endocarditis in acute stroke setting is hard to discover. Material and methods: A 75-year-old man referred to hospital for the onset of left hemiparesis and dysarthria. His past medical history included hypertension. He had 3 months history of fatigue, fever, and weight loss. Neurological examination revealed left hemiparesis and dysarthria.
Source: Journal of Stroke and Cerebrovascular Diseases - January 17, 2019 Category: Neurology Authors: Marisa Distefano, Rosalinda Calandrelli, Vincenzo Arena, Alessandro Pedicelli, Giacomo Della Marca, Fabio Pilato Tags: Case Report Source Type: research
Diagnostic Performances of the Susceptibility Vessel Sign on MRI for the Prediction of Macroscopic Thrombi Features in Acute Ischemic Stroke
In 20% –40% of cases the etiology of acute ischemic stroke (AIS) remains uncertain despite complete diagnostic investigation.1 Correlations between the histological microscopic features of the thrombus and the TOAST (Trial of Org 10 172 in Acute Stroke Treatment) categories have been found.2–5 However, from the macroscopic point of view, only one case report has considered the chromatic visual aspect of the retrieved thrombus.6 Recently, the “white” visual aspect of the thrombus at the moment of withdrawal has been related to atypical etiologies, in particular infective endocarditis.
Source: Journal of Stroke and Cerebrovascular Diseases - August 20, 2020 Category: Neurology Authors: Romain Bourcier, Zo é Duchmann, Alessandro Sgreccia, Hubert Desal, Giuseppe Carità, Jean Philippe Desilles, Bertrand Lapergue, Arturo Consoli Source Type: research
Intravenous Thrombolysis in Acute Ischemic Stroke Patients with Unsuspected Infective Endocarditis
Infective endocarditis (IE) is considered to be an absolute contraindication for intravenous tissue plasminogen activator treatment (IVtPA) in acute ischemic stroke (AIS). However, during the hyperacute stroke evaluation, the exclusion of IE may be difficult. We sought to report the prevalence of undiagnosed IE in AIS patients who received IVtPA.
Source: Journal of Stroke and Cerebrovascular Diseases - December 23, 2020 Category: Neurology Authors: Mangala Gopal, Sushil Lakhani, Vivien H. Lee Tags: Case Report Source Type: research
Fatal Intracranial Hemorrhage after Intravenous Thrombolytic Therapy for Acute Ischemic Stroke Associated with Cancer-related Nonbacterial Thrombotic Endocarditis
Nonbacterial thrombotic endocarditis (NBTE) is associated with hypercoagulability in patients with inflammatory states such as cancer and autoimmune diseases. Cardiac vegetations caused by NBTE often lead to life-threatening systemic thromboembolism that most frequently affects the brain, spleen, and kidneys. A 54-year-old woman diagnosed with ovarian cancer suddenly developed back pain and left hemiparesis. Although intravenous alteplase (rt-PA) therapy was administered to treat hyperacute ischemic infarction detected by magnetic resonance imaging, intracranial hemorrhage occurred in the left hemisphere several hours late...
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2014 Category: Neurology Authors: Takuya Yagi, Kie Takahashi, Mariko Tanikawa, Morinobu Seki, Takato Abe, Norihiro Suzuki Tags: Case Reports Source Type: research
An Uncommon Cause of Stroke: Non-bacterial Thrombotic Endocarditis
Our objective is to present the case of an uncommon but probably under-recognized cause of stroke: Non-bacterial thrombotic endocarditis (NBTE). A 59-year-old man presented to our hospital with multiple bihemispheric infarcts despite taking rivaroxaban for pulmonary emboli diagnosed 2 weeks earlier. The patient's symptoms progressed quickly and he died within a week of his initial presentation despite attempts at neuroradiologically guided clot retrieval and early recognition and treatment of disseminated intravascular coagulation.
Source: Journal of Stroke and Cerebrovascular Diseases - July 18, 2016 Category: Neurology Authors: Hilde Gundersen, Barry Moynihan Tags: Case Studies Source Type: research
Acute Ischemic Stroke Therapy in Infective Endocarditis: Case Series and Systematic Review
Objectives: To evaluate the safety of acute ischemic stroke (AIS) therapy in patients with infective endocarditis (IE) with intravenous thrombolysis (IVT) or endovascular therapy (EVT) such as mechanical thrombectomy. Methods: We conducted a retrospective study of patients who underwent AIS therapy with IVT or EVT at a tertiary referral center from 2013 to 2017, that were later diagnosed with acute IE as the causative mechanism. We then performed a systematic review of reports of acute ischemic reperfusion therapy in IE since 1995 for their success rates in terms of neurological outcome, and mortality, and their risk of he...
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2019 Category: Neurology Authors: Robert J. Marquardt, Sung-Min Cho, Prateek Thatikunta, Abhishek Deshpande, Dolora Wisco, Ken Uchino Source Type: research
Mechanical Thrombectomy in Stroke from Infective Endocarditis: Case Report and Review
To characterize outcomes after mechanical thrombectomy (MT) in patients with acute ischemic stroke (AIS) from infective endocarditis.
Source: Journal of Stroke and Cerebrovascular Diseases - November 12, 2019 Category: Neurology Authors: Kelly L. Sloane, Scott B. Raymond, James D. Rabinov, Aneesh B. Singhal Source Type: research
Management of Large Vessel Occlusion Stroke Related to Infective Endocarditis: Is Mechanical Thrombectomy a Safe Option?
Acute ischemic stroke is the most common neurological complication of infective endocarditis. Intravenous thrombolysis is contraindicated in these patients due to a higher risk of hemorrhagic complications. Whether mechanical thrombectomy has some benefit in these patients remains unanswered although some favorable results can be found in literature.
Source: Journal of Stroke and Cerebrovascular Diseases - August 20, 2020 Category: Neurology Authors: Carmen Ramos, Pablo Mayo, Santiago Trillo, Carlos G ómez-Escalonilla, Jose Luis Caniego, Manuel Moreu, Juan Vega, Santiago Rosati, Patricia Simal, Álvaro Ximénez Carrillo, Jose Antonio Egido, José Vivancos Source Type: research
Endovascular Treatment of Infective Endocarditis-Related Acute Large Vessel Occlusion Stroke
Embolic stroke is a frequent complication of infective endocarditis yet lacks acute treatment as intravenous thrombolysis should be avoided due to high risk of intracerebral hemorrhage. Mechanical thrombectomy for large vessel occlusion may be a promising treatment but there is limited data on safety outcomes in infective endocarditis.
Source: Journal of Stroke and Cerebrovascular Diseases - April 8, 2021 Category: Neurology Authors: Elie Sader, Mohamad Abdalkader, Natalie Thom, Thanh N. Nguyen, Sandra McDonald, David Greer, Stacy C. Brown, Alaa Mohamedali, Jose Gutierrez, Hang Shi, Jane Morris, Victor Lopez-Rivera, Sunil A. Sheth, Kelly L. Sloane, Aneesh Singhal, Kunakorn Atchaneeyas Source Type: research
Stroke and endocarditis: Reversing the point of view. A retrospective, cohort study
Endocarditis is a rare cause of cardioembolic ischemic or hemorrhagic stroke, leading to high mortality and morbidity.1
Source: Journal of Stroke and Cerebrovascular Diseases - January 17, 2023 Category: Neurology Authors: Irene Scala, Pier Andrea Rizzo, Paola Del Giacomo, Simone Bellavia, Giovanni Frisullo, Eleonora Rollo, Valerio Brunetti, Katleen De Gaetano Donati, Giacomo Della Marca Tags: Short Communication Source Type: research
Stroke in Non-Bacterial Thrombotic Endocarditis: 31-Year Experience (P02.023)
CONCLUSIONS: This 31-year analysis shows that stroke is a frequent complication of NBTE, has severe clinical and radiological manifestations, and high associated mortality. Anticoagulation may not prevent stroke recurrence.Disclosure: Dr. Topcuoglu has nothing to disclose. Dr. Kursun has nothing to disclose. Dr. Karatas has nothing to disclose. Dr. Buonanno has nothing to disclose. Dr. Singhal has received personal compensation as an expert witness in medicolegal cases involving stroke in young adults. Dr. Singhal's wife is an employee of Vertex Pharmaceuticals, Inc. Dr. Singhal has received research support from Pfizer and Photothera, Inc.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Topcuoglu, M., Kursun, O., Karatas, H., Buonanno, F., Singhal, A. Tags: P02 Cerebrovascular Disease II Source Type: research
Cancer-Associated Stroke: The Bergen NORSTROKE Study
Background: Underlying malignancy can cause ischemic stroke in some patients. Mechanisms include the affection of the coagulation cascade, tumor mucin secretion, infections and nonbacterial endocarditis. The release of necrotizing factor and interleukins may cause inflammation of the endothelial lining, creating a prothrombotic surface that triggers thromboembolic events, including stroke. The aims of this study were to assess the occurrence of cancer in patients who had recently suffered an ischemic stroke and to detect possible associations between stroke and cancer subtypes. Methods: All ischemic stroke patients registe...
Source: Cerebrovascular Diseases Extra - October 13, 2015 Category: Neurology Source Type: research
The Changing Epidemiology of Stroke in Acquired Immune Deficiency Syndrome (AIDS). (I7-1A)
Conclusions:There is an increased frequency of AIDS among stroke patients, possibly due to the increased detection of AIDS. In the HAART era, the median age of incident stroke in AIDS has increased. Whether HAART can reduce the incidence and improve survival of stroke needs to be explored.Disclosure: Dr. Kucab has received personal compensation for activities with Bayer HealthCare as an advisory board participant. Dr. Bhattacharya has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kucab, P., Bhattacharya, P. Tags: The Global Burden of Neurological Infections: Epidemiology, Treatment, and Prevention Data Blitz Presentations Source Type: research
The Changing Epidemiology of Stroke in Acquired Immune Deficiency Syndrome (AIDS). (P1.089)
Conclusions:There is an increased frequency of AIDS among stroke patients, possibly due to the increased detection of AIDS. In the HAART era, the median age of incident stroke in AIDS has increased. Whether HAART can reduce the incidence and improve survival of stroke needs to be explored.Disclosure: Dr. Kucab has received personal compensation for activities with Bayer HealthCare as an advisory board participant. Dr. Bhattacharya has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kucab, P., Bhattacharya, P. Tags: Neuroepidemiology: Cerebrovascular Disease Source Type: research
