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Homocysteine and non-cardiac vascular disease.
Abstract Elevated homocysteine (Hcy) levels are predictors of cardiovascular disease (CVD). Hyperhomocysteinemia has also been associated with total and CVD mortality. However, whether Hcy is just a marker or plays a causal role in CVD remains to be elucidated. In this narrative review, we discuss the associations between Hcy and non-cardiac vascular diseases, namely stroke, peripheral artery disease (PAD), carotid artery disease, chronic kidney disease (CKD), atherosclerotic renal artery stenosis (ARAS), abdominal aortic aneurysm (AAA) and erectile dysfunction (ED). The effects of several drugs on Hcy levels are ...
Source: Current Pharmaceutical Design - March 17, 2017 Category: Drugs & Pharmacology Authors: Katsiki N, Perez-Martinez P, Mikhailidis DP Tags: Curr Pharm Des Source Type: research