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Physical exercise promotes proliferation and differentiation of endogenous neural stem cells via ERK in rats with cerebral infarction.
Authors: Liu W, Wu W, Lin G, Cheng J, Zeng Y, Shi Y Abstract Physical exercise is beneficial for the functional recovery of neurons after stroke. It has been suggested that exercise regulates proliferation and differentiation of endogenous neural stem cells (NSCs); however, the underlying molecular mechanisms are still largely unknown. In the present study, the aim was to investigate whether physical exercise activates the extracellular signal‑regulated kinase (ERK) signaling pathway to promote proliferation and differentiation of NSCs in rats with cerebral infarction, thereby improving neurological function. Fol...
Source: Molecular Medicine Reports - June 15, 2018 Category: Molecular Biology Tags: Mol Med Rep Source Type: research