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Total 227 results found since Jan 2013.

Janssen Data at ASCO GU Support Ambition to Transform Treatment of Prostate and Bladder Cancer Through Precision Medicine and Early Intervention
RARITAN, N.J., February 13, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced plans to present more than 20 abstracts featuring seven oncology therapies from its robust portfolio and pipeline at the annual American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium, taking place in San Francisco on February 16-18. Building on more than a decade of leadership in the development of medicines for people diagnosed with GU cancers, Janssen will present data demonstrating its ambition to advance patient-centered treatment through precision medicine, real-world evidence a...
Source: Johnson and Johnson - February 13, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

The 3rd Beijing Forum of Evidence-Based Medicine and 2023 Cochrane China Network Symposium successfully held
Cochrane China recently hosted a virtual event for the evidence-based medicine community that brought together many of its partners, local expertise, and international speakers. Here the team provides an overview of who was involved and what was covered at the event.  The3rd Beijing forum of evidence-based medicine and Cochrane China Network  Symposium was successfully held virtually on January 15th, 2023. The host of this conference wereCochrane China Network and Beijing GRADE Center. The organizers are Centre for Evidence-based Chinese Medicine, Beijing University of Chinese Medicine, affiliate of the Cochrane China Ne...
Source: Cochrane News and Events - February 17, 2023 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Modeling of COVID ‐19 death rate using various air pollutants: A multiple linear regression approach
AbstractAir pollution is a significant health risk, especially for vulnerable populations such as children, people with chronic illnesses, the elderly, and the economically and socially disadvantaged. Furthermore, air pollution has enormous social costs that we all bear in the form of premature deaths, low productivity, sick leave, and other strains on the healthcare system. The primary sources of air pollution are traffic, home fires, and industry. Measuring NO2 levels in air pollution reveals the extent of pollution caused by traffic, particularly diesel vehicles, which are the primary source of NO2. COVID-19 rates are r...
Source: Environmental Quality Management - February 23, 2023 Category: Environmental Health Authors: Kambhampati Teja, Nirban Laskar, Ruhul Amin Mozumder Tags: RESEARCH ARTICLE Source Type: research

A survey of deep learning for MRI brain tumor segmentation methods: Trends, challenges, and future directions
ConclusionThis review's objective is to increase scholars' interest in this difficult field and familiarize them with current advancements in it. To create CAD systems aimed at brain tumor identification using MR images, digital image processing approaches, such as preprocessing, segmentation, and classification, are applied. The classic machine learning and deep learning approaches for brain tumor identification are deliberated in this work. This paper provides a summary of commonly used MR image datasets. For classification, various machine learning and deep learning algorithms have been used. This survey examines curren...
Source: Health and Technology - February 27, 2023 Category: Information Technology Source Type: research

Using Artificial Intelligence to Develop a Multivariate Model with a Machine Learning Model to Predict Complications in Mexican Diabetic Patients without Arterial Hypertension (National Nested Case-Control Study): Metformin and Elevated Normal Blood Pressure Are Risk Factors, and Obesity Is Protective
In conclusion, the results we have obtained show that artificial intelligence is a powerful and feasible tool to use for this type of study. However, we suggest that more studies be conducted to verify and elaborate upon our findings.PMID:36846513 | PMC:PMC9949947 | DOI:10.1155/2023/8898958
Source: Cancer Control - February 27, 2023 Category: Cancer & Oncology Authors: Sergio A Zaizar-Fregoso Agustin Lara-Esqueda Carlos M Hern ández-Suarez Josuel Delgado-Enciso Arturo Garcia-Nevares Luis M Canseco-Avila Jose Guzman-Esquivel Iram P Rodriguez-Sanchez Margarita L Martinez-Fierro Gabriel Ceja-Espiritu Hector Ochoa-D íaz-L Source Type: research

A survey of deep learning for MRI brain tumor segmentation methods: Trends, challenges, and future directions
ConclusionThis review's objective is to increase scholars' interest in this difficult field and familiarize them with current advancements in it. To create CAD systems aimed at brain tumor identification using MR images, digital image processing approaches, such as preprocessing, segmentation, and classification, are applied. The classic machine learning and deep learning approaches for brain tumor identification are deliberated in this work. This paper provides a summary of commonly used MR image datasets. For classification, various machine learning and deep learning algorithms have been used. This survey examines curren...
Source: Health and Technology - February 27, 2023 Category: Information Technology Source Type: research

Acori Tatarinowii Rhizoma: A comprehensive review of its chemical composition, pharmacology, pharmacokinetics and toxicity
Acori Tatarinowii Rhizoma (ATR, Shi Chang Pu in Chinese), a natural product with multiple targets in various diseases. This review provides the comprehensive summary of the chemical composition, pharmacological effects, pharmacokinetics parameters and toxicity of ATR. The results indicated that ATR possesses a wide spectrum of chemical composition, including volatile oil, terpenoids, organic acids, flavonoids, amino acids, lignin, carbohydrates and so on. Accumulating evidence from various studies has shown that ATR exerts a wide range of pharmacological properties, including protecting nerve cells, alleviating learning an...
Source: Frontiers in Pharmacology - March 16, 2023 Category: Drugs & Pharmacology Source Type: research

Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol
Stephanie Blendermann, 65, had good reason to worry about heart disease. Three of her sisters died in their 40s or early 50s from heart attacks, and her father needed surgery to bypass clogged arteries. She also suffered from an autoimmune disorder that results in chronic inflammation and boosts the odds of developing cardiovascular illnesses. “I have an interesting medical chart,” says Blendermann, a real estate agent in Prior Lake, Minnesota. Yet Blendermann’s routine lab results weren’t alarming. At checkups, her low-density lipoprotein (LDL), or “bad,” cholesterol hovered around the 100 milligrams-per-...
Source: Science of Aging Knowledge Environment - March 16, 2023 Category: Geriatrics Source Type: research

ERLEADA ® (apalutamide), First-and-Only Next-Generation Androgen Receptor Inhibitor with Once-Daily, Single-Tablet Option, Now Available in the U.S.
HORSHAM, Pa., April 3, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the availability of an additional tablet strength of ERLEADA® (apalutamide) in the United States. The introduction of the 240mg tablet provides the first-and-only option for a once-daily, single-tablet Androgen Receptor Inhibitor (ARI) approved for the treatment of patients with non-metastatic castration-resistant prostate cancer (nmCRPC) and for the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC).With two strengths available, healthcare professionals will have the flexibility to...
Source: Johnson and Johnson - April 3, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Social Determinants of Health and Racial Disparities in Cardiac Events in Breast Cancer
CONCLUSIONS: Neighborhood and built environment variables are the most important SDOH predictors for 2-year MACE, and NHB patients were more likely to have unfavorable SDOH conditions. This finding reinforces that race is a social construct.PMID:37433439 | DOI:10.6004/jnccn.2023.7023
Source: Journal of the National Comprehensive Cancer Network : JNCCN - July 11, 2023 Category: Cancer & Oncology Authors: Nickolas Stabellini Mantas Dmukauskas Marcio S Bittencourt Jennifer Cullen Amie J Barda Justin X Moore Susan Dent Husam Abdel-Qadir Aniket A Kawatkar Ambarish Pandey John Shanahan Jill S Barnholtz-Sloan Kristin A Waite Alberto J Montero Avirup Guha Source Type: research