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Different associations between HDL cholesterol and cardiovascular diseases in people with diabetes mellitus and people without diabetes mellitus: a prospective community-based study
CONCLUSIONS: High HDL-cholesterol concentrations were paradoxically associated with high risk of composite CVD outcomes in individuals with or without DM. However, low HDL-cholesterol concentrations failed to predict future CVD risk in individuals with DM.PMID:34019626 | DOI:10.1093/ajcn/nqab163
Source: Am J Clin Nutr - May 21, 2021 Category: Nutrition Authors: Zhijun Wu Zhe Huang Alice H Lichtenstein Cheng Jin Shuohua Chen Shouling Wu Xiang Gao Source Type: research

Skipping breakfast before and during early pregnancy and incidence of gestational diabetes mellitus: the Japan Environment and Children's Study.
CONCLUSIONS: Breakfast consumption <3 times/wk before and during early pregnancy, compared with daily consumption, was associated with an increased odds of developing GDM. PMID: 32020171 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - February 4, 2020 Category: Nutrition Authors: Dong JY, Ikehara S, Kimura T, Cui M, Kawanishi Y, Kimura T, Ueda K, Iso H, Japan Environment and Children's Study Group Tags: Am J Clin Nutr Source Type: research

Nutritional regulation of coupling factor 6, a novel vasoactive and proatherogenic peptide
High sodium, high glucose, and obesity are important risk factors for age-related diseases such as cardiovascular disease, stroke and cancer. Coupling factor 6 (CF6) is released from vascular endothelial cells and functions as a circulating peptide that inhibits prostacyclin and nitric oxide generation by intracellular acidosis. High glucose elevates CF6 by activation of protein kinase C and p38 mitogen-activated protein kinase, whereas CF6 causes type 2 diabetes mellitus, resulting in a vicious cycle by high glucose.
Source: Nutrition - August 5, 2016 Category: Nutrition Authors: Tomohiro Osanai, Kasumi Mikami, Maiko Kitajima, Mayumi Urushizaka, Kumiko Kawasaki, Toshiko Tomisawa, Chieko Itaki, Yuka Noto, Koji Magota Tags: Review Article Source Type: research

Evidence-Based Guideline of the German Nutrition Society: Fat Intake and Prevention of Selected Nutrition-Related Diseases
As nutrition-related chronic diseases have become more and more frequent, the importance of dietary prevention has also increased. Dietary fat plays a major role in human nutrition, and modification of fat and/or fatty acid intake could have a preventive potential. The aim of the guideline of the German Nutrition Society (DGE) was to systematically evaluate the evidence for the prevention of the widespread diseases obesity, type 2 diabetes mellitus, dyslipoproteinaemia, hypertension, metabolic syndrome, coronary heart disease (CHD), stroke, and cancer through the intake of fat or fatty acids. The main results can be summar...
Source: Annals of Nutrition and Metabolism - September 28, 2015 Category: Nutrition Source Type: research