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Infectious Disease: Human Papillomavirus (HPV)
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De-Escalation Treatment for Human Papillomavirus-Related Oropharyngeal Cancer: Questions for Practical Consideration
Oncology (Williston Park). 2023 Jul 21;37(7):281-287. doi: 10.46883/2023.25921000.ABSTRACTHuman papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (SCC), which accounts for an increasing proportion of all head and neck cancers, represents a specific entity with distinct clinical and molecular characteristics. It is now firmly established that patients with HPV-positive oropharyngeal SCC have a significantly improved prognosis because this variant has exquisite radiosensitivity compared with HPV-negative oropharyngeal SCC; thus, it can be targeted with de-escalated approaches using reduced doses of radiatio...
Source: Oncology (Williston Park, N.Y.) - July 27, 2023 Category: Cancer & Oncology Authors: Allen M Chen Source Type: research
