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Silencing of Fli1 gene mimics effects of preeclampsia and induces collagen synthesis in human umbilical arteries
CONCLUSIONS: Our results show that after silencing the Fli1 gene in healthy human umbilical arteries a new phenotype emerges which is typical for preeclampsia and is associated with vascular fibrosis.PMID:35569064 | DOI:10.1093/ajh/hpac065
Source: American Journal of Hypertension - May 15, 2022 Category: Cardiology Authors: Natalia I Agalakova Vitaly A Reznik Ivan A Ershov Ekaterina A Lupanova Olga V Nadei Dmitry O Ivanov C David Adair Alexei Y Bagrov Source Type: research

Azelnidipine Inhibits the Differentiation and Activation of THP-1 Macrophages through the L-Type Calcium Channel.
CONCLUSION: Our results suggest that azelnidipine has potent antiatherosclerotic properties by inhibition of macrophage activation through Cav1.2. PMID: 29398679 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - February 7, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research