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Specialty: Biology
Source: Fish and Shellfish Immunology
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Total 31 results found since Jan 2013.
Molecular characterization of a RNA polymerase (RNAP) II (DNA directed) polypeptide H (POLR2H) in Pacific white shrimp (Litopenaeus vannamei) and its role in response to high-pH stress
Publication date: Available online 9 December 2019Source: Fish & Shellfish ImmunologyAuthor(s): Zhi-Zhan Luo, Hui-Ming Sun, Jing-Wen Guo, Peng Luo, Chao-Qun Hu, Wen Huang, Hu ShuAbstractRNA polymerase (RNAP) II (DNA-directed) (POLR2) genes are essential for cell viability under environmental stress and for the transfer of biological information from DNA to RNA. However, the function and characteristics of POLR2 genes in crustaceans are still unknown. In the present study, a POLR2H cDNA was isolated from Pacific white shrimp (Litopenaeus vannamei) and designated as Lv-POLR2H. The full-length Lv-POLR2H cDNA is 772 bp in leng...
Source: Fish and Shellfish Immunology - December 11, 2019 Category: Biology Source Type: research
L-carnitine regulated Nrf2/Keap1 activation in vitro and in vivo and protected oxidized fish oil-induced inflammation response by inhibiting the NF-κB signaling pathway in Rhynchocypris lagowski Dybowski
In conclusion, l-carnitine regulated Nrf2/Keap1 activation in vitro and in vivo and protected oxidized fish oil-induced inflammation response by inhibiting the NF-κB signaling pathway in Rhynchocypris lagowski Dybowski.
Source: Fish and Shellfish Immunology - September 6, 2019 Category: Biology Source Type: research
Functional characterization of seven-band grouper immunoglobulin like cell adhesion molecule, Nectin4 as a cellular receptor for nervous necrosis virus
Publication date: October 2019Source: Fish & Shellfish Immunology, Volume 93Author(s): Rahul Krishnan, Syed Shariq Nazir Qadiri, Myung-Joo OhAbstractNectin-4/PVRL4 belonging to the family of immunoglobulin-like cell adhesion molecules was identified as a potential cellular receptor for several animal viruses. Here we show that nervous necrosis virus that causes viral nervous necrosis in teleosts uses the same receptor in its life cycle. Transfection of SSN-1 cell lines with an expression vector encoding Nectin-4 rendered them to be more susceptible to NNV. Immunofluorescence microscopy on Nectin-4 expressing cells reveal...
Source: Fish and Shellfish Immunology - August 20, 2019 Category: Biology Source Type: research
The first cloned echinoderm tumor necrosis factor receptor from Holothuria leucospilota: Molecular characterization and functional analysis
This study provides evidences for the potential roles of sea cucumber TNFR in the innate immunity.
Source: Fish and Shellfish Immunology - August 8, 2019 Category: Biology Source Type: research
Molecular cloning of Y-Box binding protein-1 from mandarin fish and its roles in stress-response and antiviral immunity
Publication date: October 2019Source: Fish & Shellfish Immunology, Volume 93Author(s): Jian He, Tao-Lin Xie, Xiao Li, Yang Yu, Zhi-Peng Zhan, Shao-Ping Weng, Chang-Jun Guo, Jian-Guo HeAbstractMandarin fish (Siniperca chuatsi) is a universally farmed fish species in China and has a large farming scale and economic value. With the high-density cultural mode in mandarin fish, viral diseases, such as infectious spleen and kidney necrosis virus (ISKNV) and Siniperca chuatsi rhabdovirus (SCRV), have increased loss, which has seriously restricted the development of aquaculture. Y-Box binding protein 1 (YB-1) is a member of cold s...
Source: Fish and Shellfish Immunology - August 3, 2019 Category: Biology Source Type: research
Litopenaeus vannamei Src64B restricts white spot syndrome virus replication by modulating apoptosis
In conclusion, the current data strongly suggest that Src64B is a host factor that inhibits WSSV replication by modulating apoptosis in shrimp.
Source: Fish and Shellfish Immunology - July 28, 2019 Category: Biology Source Type: research
Inhibition of Cyclophilin A on the replication of red spotted grouper nervous necrosis virus associates with multiple pro-inflammatory factors
Publication date: Available online 5 June 2019Source: Fish & Shellfish ImmunologyAuthor(s): Muhammad Asim, V. Sarath Babu, Zhendong Qin, Lijuan Zhao, Jianguo Su, Jun Li, Jiagang Tu, Hongyan Kou, Li LinAbstractCyclophilin A (CypA) is a ubiquitously expressed cellular protein and involves in diverse pathological conditions, including infection and inflammation. CypA acts as a key factor in the replication of several viruses. However, little is known about the role of CypA in the replication of the red-spotted grouper nervous necrosis virus (RGNNV). In the present report, grouper CypA (GF-CypA) was cloned from the grouper fin...
Source: Fish and Shellfish Immunology - June 6, 2019 Category: Biology Source Type: research
Rac1 GTPase is a critical factor in phagocytosis in the large yellow croaker Larimichthys crocea by interacting with tropomyosin
Publication date: Available online 11 May 2019Source: Fish & Shellfish ImmunologyAuthor(s): Fang Han, Wanbo Li, Xiande Liu, Dongling Zhang, Lanping Liu, Zhiyong WangAbstractThe Rho family GTPase Rac1 acts as a molecular switch for signal transduction to regulate various cellular functions. Here, a Rac1 homolog (LcRac1) was identified in large yellow croaker (Larimichthys crocea), one of the most economically important marine fishes. The LcRac1 protein was expressed in Escherichia coli and purified. Subsequently the specific antibody was raised using the purified fusion protein (GST-LcRac1). LcRac1 was ubiquitously expresse...
Source: Fish and Shellfish Immunology - May 16, 2019 Category: Biology Source Type: research
PMA-triggered PKCε activity enhances Nrf2-mediated antiviral response on fish rhabdovirus infection
Publication date: April 2019Source: Fish & Shellfish Immunology, Volume 87Author(s): Yun-Fei Dang, Tian-Xiu Qiu, Da-Wei Song, Lei LiuAbstractViral infection is often accompanied with alteration of intracellular redox state, especially an imbalance between reactive oxygen species (ROS) production and antioxidant cellular defenses. The previous studies showed that an antioxidant cellular defense system, the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2), played an important role against spring viraemia of carp virus (SVCV) infection in fish. To further reveal the mediated mechanism that Nrf2 active s...
Source: Fish and Shellfish Immunology - February 26, 2019 Category: Biology Source Type: research
Molecular cloning and preliminary functional analysis of six RING-between-ring (RBR) genes in grass carp (Ctenopharyngodon idellus)
Publication date: April 2019Source: Fish & Shellfish Immunology, Volume 87Author(s): Lifei Luo, Denghui Zhu, Rong Huang, Lv Xiong, Rumana Mehjabin, Libo He, Lanjie Liao, Yongming Li, Zuoyan Zhu, Yaping WangAbstractUbiquitination is a post-translational modification of proteins that is widely present in eukaryotic cells. There is increasing evidence that ubiquitinated proteins play crucial roles in the immune response process. In mammals, RING-between-RING (RBR) proteins play a key role in regulating immune signaling as the important E3 ubiquitin ligases during ubiquitination. However, the function of RBR in fish is still u...
Source: Fish and Shellfish Immunology - January 9, 2019 Category: Biology Source Type: research
Molecular cloning and functional characterization of a short peptidoglycan recognition protein from triangle-shell pearl mussel (Hyriopsis cumingii)
In this study, we cloned and functionally analyzed a short PGRP (HcPGRP2) from the triangle-shell pearl mussel Hyriopsis cumingii. The full-length cDNA sequence of HcPGRP2 gene was 1185 bp containing an open reading frame of 882 bp encoding a 293 amino acid protein. HcPGRP2 was predicted to have two SH3b domains and a conserved C-terminal PGRP domain. Quantitative real-time RT-PCR showed that HcPGRP2 was expressed in all examined tissues and its expression was induced most significantly by Staphylococcus aureus and Vibrio parahaemolyticus in the hepatopancreas and gills. RNA interference by siRNA results revealed that HcPG...
Source: Fish and Shellfish Immunology - December 7, 2018 Category: Biology Source Type: research
Molecular characterization of p38 MAPK from blunt snout bream (Megalobrama amblycephala) and its expression after ammonia stress, and lipopolysaccharide and bacterial challenge
Publication date: January 2019Source: Fish & Shellfish Immunology, Volume 84Author(s): Chun-Nuan Zhang, Samad Rahimnejad, Kang-Le Lu, Wen-Hao Zhou, Ji-Liang ZhangAbstractp38 mitogen-activated protein kinase (MAPK) is an important protein which plays a key role in regulating the innate immunity, so exploring its molecular characterization is helpful in understanding the resistance against microbial infections in cultured fish. Here, a full-length cDNA of p38 MAPK was cloned from liver of blunt snout bream (Megalobrama amblycephala) which covered 2419 bp with an open reading frame of 1086 bp encoding 361 amino acids. p38 MAP...
Source: Fish and Shellfish Immunology - November 4, 2018 Category: Biology Source Type: research
MiR-214 inhibits snakehead vesiculovirus (SHVV) replication by targeting host GS
This study provided information for understanding the molecular mechanism of SHVV pathogenicity and a potential antiviral strategy against SHVV infection.
Source: Fish and Shellfish Immunology - October 9, 2018 Category: Biology Source Type: research
Identification, characterisation and preliminary functional analysis of IRAK-M in grass carp (Ctenopharyngodon idella)
Publication date: Available online 2 October 2018Source: Fish & Shellfish ImmunologyAuthor(s): Pengfei Chu, Libo He, Denghui Zhu, Liangming Chen, Rong Huang, Lanjie Liao, Yongming Li, Zuoyan Zhu, Yaping WangAbstractInterleukin-1 receptor-associated kinase (IRAK) family members play important roles in myeloid differentiation primary response 88 (MyD88)-dependent toll-like receptor (TLR) signaling, the crucial innate immune pathway in vertebrates. In the present study, the IRAK family gene IRAK-M (also called IRAK3) from grass carp (Ctenopharyngodon idella) was cloned and characterised. IRAK-M was mainly enriched in the sple...
Source: Fish and Shellfish Immunology - October 5, 2018 Category: Biology Source Type: research
A mannose receptor is involved in the anti-Vibrio defense of red swamp crayfish
Publication date: Available online 9 August 2018Source: Fish & Shellfish ImmunologyAuthor(s): Xin Man, Xin-Tong Pan, Hong-Wei Zhang, Yue Wang, Xin-Cang Li, Xiao-Wen ZhangAbstractMannose receptor (MR), a member of pattern-recognition receptors (PRRs), is the first MR family member to be discovered that plays a critical role in immunity. The function of MRs has been reported in mammals and teleosts while none in invertebrates. In the present study, we identified a MR-like gene (designated as PcMR) from red swamp crayfish, Procambarus clarkii. The PcMR cDNA is 6848 bp long with a 6288 bp open reading frame that encodes a poly...
Source: Fish and Shellfish Immunology - August 10, 2018 Category: Biology Source Type: research
