Filtered By:
Specialty: Reproduction Medicine
Drug: Melatonin
This page shows you your search results in order of date.
Order by Relevance | Date
Total 2 results found since Jan 2013.
Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway
CONCLUSIONS: These findings suggest that SIRT1 pathway plays essential roles in the pleiotropic actions of melatonin on Leydig cells and in the prevention of hyperglycaemia-induced steroidogenic dysfunction. The stimulatory action of melatonin on SIRT1 pathway is related to oxidative stress and its antioxidant property. Our data provide new evidence for the relationship of melatonin and SIRT1 pathway in the context of hyperglycaemia, and melatonin as a combination therapy may be useful to combat DM-related complications, especially male reproductive system injury.PMID:35962432 | DOI:10.1186/s12958-022-00991-6
Source: Reproductive Biology - August 12, 2022 Category: Reproduction Medicine Authors: Ping Wang Shoubing Zhang Shuai Lin Zhengmei Lv Source Type: research
