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Specialty: Reproduction Medicine
Drug: Medroxyprogesterone

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NLRP7 contributes to in vitro decidualization of endometrial stromal cells.
CONCLUSIONS: NLRP7 was upregulated and translocated to the nucleus of the endometrial stromal cells in an in vitro decidualization model. Overexpressed NLRP7 promoted the IGFBP-1 expression and PR reporter activation. IGFBP-1 expression decreased with the knockdown of NLRP7. Therefore, we suggest that NLRP7 contributes to in vitro decidualization of endometrial stromal cells. PMID: 28810880 [PubMed - in process]
Source: Reproductive Biology - August 15, 2017 Category: Reproduction Medicine Authors: Huang JY, Yu PH, Li YC, Kuo PL Tags: Reprod Biol Endocrinol Source Type: research