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Specialty: Surgery
Cancer: Pancreatic Cancer
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Total 2 results found since Jan 2013.
Hypoxia induces the overexpression of microRNA-21 in pancreatic cancer cells
Conclusions: MiR-21 is induced by hypoxia in pancreatic cancer cells via HIF-1α upregulation. MiR-21 overexpression allows cells to avoid apoptosis in a hypoxic microenvironment. Inhibition of miR-21 expression may increase cellular susceptibility to hypoxia in pancreatic cancer.
Source: Journal of Surgical Research - May 20, 2013 Category: Surgery Authors: Thomas A. Mace, Amy L. Collins, Sylwia E. Wojcik, Carlo M. Croce, Gregory B. Lesinski, Mark Bloomston Tags: Gastrointestinal Source Type: research
