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Total 76 results found since Jan 2013.

Naringenin attenuates cerebral ischemia/reperfusion injury by inhibiting oxidative stress and inflammatory response via the activation of SIRT1/FOXO1 signaling pathway in vitro
CONCLUSIONS: Naringenin protected HT22 cells against OGD/R injury depending on its antioxidant and anti-inflammatory activities via promoting the SIRT1/FOXO1 signaling pathway.PMID:37132753 | PMC:PMC10158850 | DOI:10.1590/acb380823
Source: Acta Cirurgica Brasileira - May 3, 2023 Category: Surgery Authors: Peng Zhao Yi Lu Zhiyun Wang Source Type: research

pfeRNAs —A Novel Class of Small Non-coding RNAs With Real Translational Potential
Small non-coding RNAs (sncRNAs) are defined by being less than 200 nucleotides (nt) in length, and consequently, have been divided into many different subclasses including mature microRNA (miRNA), small interfering RNA (siRNA), piwi-interacting RNA (piRNA), protein functional effector sncRNA (pfeRNA), precursor miRNA (pre-miRNA), small nucleolar RNA (snoRNA), 5S ribosome RNA (5SrRNA), 5.8SrRNA, and small nuclear RNA (snRNA). Except for the class of pfeRNAs, the discovery, identification, biogenesis, characterization, and function of other sncRNAs have been well documented.
Source: Journal of Surgical Research - January 2, 2023 Category: Surgery Authors: Yuping Mei, Hamza Khan, Maria Shishikura, Shun Ishiyama, Ali Khan, Hajime Orita, Malcolm V. Brock Tags: Surgical Oncology Source Type: research

Intrauterine exposure to oxidative stress induces caspase-1-dependent enteric nerve cell pyroptosis
ConclusionOxidative stress can induce the death of enteric nerve cells by activating caspase-1-dependent pyroptosis through NLRP3 inflammasomes, which may contribute to abnormal enteric nervous system development.
Source: Pediatric Surgery International - September 30, 2022 Category: Surgery Source Type: research

Inhibiting Interleukin-6/Signal Transducers and Activators of Transduction-3/Hypoxia-Inducible Factor-1 α Signaling Pathway Suppressed the Growth of Infantile Hemangioma
Conclusion Our findings indicate that inhibiting the IL-6/STAT3/HIF-1α signaling pathways could suppress IH growth. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: European Journal of Pediatric Surgery - July 12, 2022 Category: Surgery Authors: Maimaiti, Aziguli Aierken, Yeerfan Zhou, Ling He, Jun Abudureyimu, Abudusaimi Li, Shui-Xue Tags: Original Article Source Type: research