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Specialty: Orthopaedics
Source: European Spine Journal
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Total 3 results found since Jan 2013.
Cyclin-dependent kinase 12 (CDK12) in chordoma: prognostic and therapeutic value
ConclusionHigh expression of CDK12 is an independent predictor of poor prognosis in chordoma. Inhibition of CDK12 significantly decreased chordoma cell proliferation and induced apoptosis. Our results support CDK12 as a novel prognostic biomarker and therapeutic target in chordoma.
Source: European Spine Journal - July 19, 2020 Category: Orthopaedics Source Type: research
Down-regulated expression of vimentin induced by mechanical stress in fibroblasts derived from patients with ossification of the posterior longitudinal ligament
Conclusion
The down-regulation of vimentin induced by mechanical stress plays an important role in the progression of OPLL through the induction of osteogenic differentiation in OPLL cells.
Source: European Spine Journal - October 30, 2014 Category: Orthopaedics Source Type: research
The effect of noggin interference in a rabbit posterolateral spinal fusion model
Conclusions
Early noggin suppression does not appear to enhance the BMP activity sufficiently to significantly affect final fusion rates in our model.
Source: European Spine Journal - October 30, 2014 Category: Orthopaedics Source Type: research
