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Specialty: Allergy & Immunology
Source: Allergy, Asthma and Immunology Research
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Total 102 results found since Jan 2013.
Epithelial CST1 Promotes Airway Eosinophilic Inflammation in Asthma via the AKT Signaling Pathway
CONCLUSIONS: Increased sputum CST1 may play a key role in the pathogenesis of asthma through involvement in eosinophilic and type 2 inflammation through activation of the AKT signaling pathway, further promoting SERPINB2 expression. Therefore, targeting CST1 might be of therapeutic value in treating asthma with severe and eosinophilic phenotypes.PMID:37075800
Source: Allergy, Asthma and Immunology Research - April 19, 2023 Category: Allergy & Immunology Authors: Lijuan Du Changyi Xu Kun Tang Jia Shi Lu Tang Xiao Lisha Chengcheng Lei Huicong Liu Yuxia Liang Yubiao Guo Source Type: research
IL-24 Contributes to Neutrophilic Asthma in an IL-17A-Dependent Manner and Is Suppressed by IL-37
CONCLUSIONS: IL-24 aggravated neutrophilic airway inflammation by increasing epithelium-derived IL-17A production, which could be suppressed by IL-37. Targeting the IL-24/IL-17A signaling axis is a potential strategy, and IL-37 is a potential candidate agent for alleviating neutrophilic airway inflammation in asthma.PMID:36174993 | DOI:10.4168/aair.2022.14.5.505
Source: Allergy, Asthma and Immunology Research - September 29, 2022 Category: Allergy & Immunology Authors: Kang-Ni Feng Ping Meng Min Zhang Xiao-Ling Zou Shuang Li Chu-Qin Huang Ke-Fang Lai Hong-Tao Li Tian-Tuo Zhang Source Type: research
