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Specialty: Cytology
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Total 5 results found since Jan 2013.
Contribution of TRPC channels in human and experimental pulmonary arterial hypertension
Am J Physiol Lung Cell Mol Physiol. 2023 Jun 27. doi: 10.1152/ajplung.00011.2023. Online ahead of print.ABSTRACTPulmonary arterial hypertension (PAH) is due to progressive distal pulmonary artery (PA) obstruction leading to right ventricular hypertrophy and failure. Exacerbated store-operated Ca2+ entry (SOCE) contributes to PAH pathogenesis, mediating human PA smooth muscle cells (hPASMCs) abnormalities. The transient receptor potential canonical channels (TRPC family) are Ca2+-permeable channels contributing to SOCE in different cell types, including PASMCs. However, the properties, signaling pathways, and contribution t...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - June 27, 2023 Category: Cytology Authors: Bastien Masson Ana ïs Saint-Martin Willer Mary Dutheil Lucille Penalva H élène Le Ribeuz Kristelle El Jekmek Yann Ruchon Sylvia Cohen-Kaminsky Jessica Sabourin Marc Humbert Olaf Mercier David Montani V éronique Capuano Fabrice Antigny Source Type: research
