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Heat shock transcription factor 2 predicts mucosal healing and promotes mucosal repair of ulcerative colitis.
Conclusions: HSF2 may be a predictor of MH in UC patients. HSF2 inhibited inflammation and promoted mucosal repair. PMID: 32538201 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - June 18, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Downregulation of LncRNA-RP11-317J10.2 promotes cell proliferation and invasion and predicts poor prognosis in colorectal cancer.
CONCLUSIONS: This study reveals a crucial role for lncRNA-RP11-317J10.2 in CRC growth and invasion via upregulation of cyclin D1 expression and suggests that expression of this lncRNA may be a potential prognostic biomarker for CRC. PMID: 29073791 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - October 28, 2017 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

The role of MALAT-1 in the invasion and metastasis of gastric cancer.
CONCLUSIONS: MALAT-1 may promote the migration and invasion of GC cells in part by regulating EMT. PMID: 28276823 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - March 11, 2017 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Knockdown of asparagine synthetase (ASNS) suppresses cell proliferation and inhibits tumor growth in gastric cancer cells.
CONCLUSION: ASNS may contribute to gastric cancer tumorigenesis and may represent a novel therapeutic target for prevention or intervention of gastric cancer. PMID: 27251594 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - June 3, 2016 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Potential role of TRIM3 as a novel tumour suppressor in colorectal cancer (CRC) development.
Conclusions TRIM3 functions as a tumour suppressor in CRC progression. This tumour-suppressive function is exerted partially through regulation of p53 protein. Therefore, this protein may represent a novel therapeutic target for prevention or intervention of CRC. PMID: 26691157 [PubMed - in process]
Source: Scandinavian Journal of Gastroenterology - February 14, 2016 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research