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Yangonin protects against estrogen-induced cholestasis in a farnesoid X receptor-dependent manner.
In conclusion, yangonin alleviates estrogen-induced cholestasis, due to FXR-mediated gene regulation. PMID: 31220436 [PubMed - as supplied by publisher]
Source: European Journal of Pharmacology - June 16, 2019 Category: Drugs & Pharmacology Authors: Dong R, Wang J, Gao X, Wang C, Liu K, Wu J, Liu Z, Sun H, Ma X, Meng Q Tags: Eur J Pharmacol Source Type: research

Licorice Root Components in Dietary Supplements are Selective Estrogen Receptor Modulators with a Spectrum of Estrogenic and Anti-Estrogenic Activities
Publication date: Available online 26 November 2015 Source:Steroids Author(s): Nittaya Boonmuen, Ping Gong, Zulfiqar Ali, Amar G. Chittiboyina, Ikhlas Khan, Daniel R. Doerge, William G. Helferich, Kathryn E. Carlson, Teresa Martin, Pawinee Piyachaturawat, John A. Katzenellenbogen, Benita S. Katzenellenbogen Licorice root extracts are often consumed as botanical dietary supplements by menopausal women as a natural alternative to pharmaceutical hormone replacement therapy. In addition to their components liquiritigenin (Liq) and isoliquiritigenin (Iso-Liq), known to have estrogenic activity, licorice root extra...
Source: Steroids - November 27, 2015 Category: Drugs & Pharmacology Source Type: research