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Specialty: Drugs & Pharmacology
Countries: Japan Health
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Total 63 results found since Jan 2013.
Seeking an Important Role on Metabolomics-Effects of β-Estradiol on Lipoprotein Metabolism in Mammary Tumors
Yakugaku Zasshi. 2022;142(11):1191-1199. doi: 10.1248/yakushi.22-00098.ABSTRACTThe role of β-estradiol (E2) in lipoprotein metabolism in mammary tumors remains unknown. Therefore the effect of E2 on secretion of lipoprotein lipase (LPL) from mouse mammary tumor FM3A cells was examined. The E2-treated FM3A cells increased active LPL secretion in a time- and dose-dependent manner. The activity of mitogen-activated protein kinase (MAPK) was elevated in the tumor cells treated with E2, and E2-stimulated secretion of LPL was suppressed by the MAPK kinase 1/2 inhibitor PD98059, extracellular signal-regulated kinase (ERK) 1/2 in...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - November 3, 2022 Category: Drugs & Pharmacology Authors: Tetsuo Morita Source Type: research
