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Source: Cellular Signalling
Procedure: Carotid Angioplasty

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Total 1 results found since Jan 2013.

Preferential Secretion of Collagen Type 3 versus Type 1 from Adventitial Fibroblasts Stimulated by TGF-β/Smad3-Treated Medial Smooth Muscle Cells.
Abstract Restenosis, or arterial lumen re-narrowing, occurs in 30-50 % of the patients undergoing angioplasty. Adaptive remodeling is compensatory enlargement of the vessel size, and has been reported to prevent the deleterious effects of restenosis. Our previous studies have shown that elevated transforming growth factor (TGF-β) and its signaling protein Smad3 in the media layer induce adaptive remodeling of angioplastied rat carotid artery accompanying an increase of total collagen in the adventitia. In order to gain insights into a possible role of collagen in Smad3-induced adaptive remodeling, here we have in...
Source: Cellular Signalling - December 29, 2012 Category: Cytology Authors: Goel SA, Guo LW, Shi XD, Kundi R, Sovinski G, Seedial S, Liu B, Kent KC Tags: Cell Signal Source Type: research