Filtered By:
Source: J Cell Mol Med
Procedure: Kidney Transplant
This page shows you your search results in order of date.
Order by Relevance | Date
Total 1 results found since Jan 2013.
Bortezomib alleviates antibody-mediated rejection in kidney transplantation by facilitating Atg5 expression
J Cell Mol Med. 2021 Nov 3. doi: 10.1111/jcmm.16998. Online ahead of print.ABSTRACTAntibody-mediated rejection (AMR) is one of the most dominant mechanisms responsible for the loss of kidney grafts. Previous researches have shown that donor-specific antibodies (DSAs) are the major mediators of AMR. In order to prolong the survival time of grafts, it is vital to reduce the incidence of AMR and inhibit the generation of DSAs. We established an animal model of AMR by performing kidney transplantation in pre-sensitized rats. Then, we investigated the effect of bortezomib (BTZ) on AMR. We found that BTZ could reduce the serum l...
Source: J Cell Mol Med - November 4, 2021 Category: Molecular Biology Authors: Hong Cheng Bin Xu Lijie Zhang Yi Wang Ming Chen Shuqiu Chen Source Type: research
