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Cancers, Vol. 13, Pages 5209: ARRDC4 and UBXN1: Novel Target Genes Correlated with Prostate Cancer Gleason Score
Byun To investigate potential markers of the prostate cancer (PCa) Gleason score (GS), genetic arrays in 841 PCa patients were conducted followed by functional validation in PCa cell lines. A total of 841 PCa patients who received radical prostatectomy (RP) from November 2003 to July 2019 were enrolled. HumanExome BeadChip 12v1-1 (Illumina, Inc.; San Diego, CA, USA) exomic arrays were performed on RP tissue samples. Unconditional logistic regression was used to calculate odds ratios to generate estimates of the relative risk of pathologic GS (≥8); SNPs with the highest association were selected and validated using P...
Source: Cancers - October 17, 2021 Category: Cancer & Oncology Authors: Jong Jin Oh Jin-Nyoung Ho Seok-Soo Byun Tags: Article Source Type: research