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Source: Clinical Prostate Cancer
Procedure: Prostatectomy

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Total 2 results found since Jan 2013.

Alanine-Serine-Cysteine Transporter 2 Inhibition Suppresses Prostate Cancer Cell Growth In Vitro
J Clin Med. 2022 Sep 16;11(18):5466. doi: 10.3390/jcm11185466.ABSTRACTAlanine-serine-cysteine transporter 2 (ASCT2) has been associated with increased levels of metabolism in various malignant tumors. However, its biological significance in the proliferation of prostate cancer (PCa) cells remains under investigation. We used the cBioPortal database to assess the effect of ASCT2 expression on the oncological outcomes of 108 PCa patients. To evaluate the function of ASCT2 in castration-sensitive PCa (CSPC) and castration-resistant PCa (CRPC), LNCaP cells and the ARV7-positive PCa cell line, 22Rv1, were assessed using cell pr...
Source: Clinical Prostate Cancer - September 23, 2022 Category: Cancer & Oncology Authors: Masanobu Saruta Kiyoshi Takahara Atsuhiko Yoshizawa Atsuko Niimi Toshiyuki Takeuchi Takuhisa Nukaya Masashi Takenaka Kenji Zennami Manabu Ichino Hitomi Sasaki Mamoru Kusaka Motoshi Suzuki Makoto Sumitomo Ryoichi Shiroki Source Type: research