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Drug: Medroxyprogesterone

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Total 120 results found since Jan 2013.

GSE200312 Glucocorticoid recptor knockdown in primary amnion epithelial cells treated with MPA and TNFa
Contributors : Sarah J Cunningham ; Terrence K Allen ; Tim E Reddy ; Alejandro BarreraSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo analyze the effect of glucocorticoids on primary amnion epthelial cells, we harvested tissue samples from 10 healthy ceseaean section patients. We knocked down the glucocorticoid receptor with an siRNA or used a control siRNA. We treated samples with medroxyprogesterone acetate. Half the cells we subjected to a TNFa challenge
Source: GEO: Gene Expression Omnibus - April 9, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Matrix Metalloproteinases in Human Decidualized Endometrial Stromal Cells
Curr Issues Mol Biol. 2021 Nov 26;43(3):2111-2123. doi: 10.3390/cimb43030146.ABSTRACTCyclic changes, such as growth, decidualization, shedding, and regeneration, in the human endometrium are regulated by the reciprocal action of female hormones, such as estradiol (E2), and progesterone (P4). Matrix metalloproteases (MMPs) and tissue inhibitors of MMPs (TIMPs) control the invasion of extravillous trophoblast cells after implantation. Several MMPs and TIMPs function in the decidua and endometrial stromal cells (ESCs). Here, we aimed to systematically investigate the changes in MMPs and TIMPs associated with ESC decidualizati...
Source: Current Issues in Molecular Biology - December 23, 2021 Category: Molecular Biology Authors: Yoji Hisamatsu Hiromi Murata Hiroaki Tsubokura Yoshiko Hashimoto Masaaki Kitada Susumu Tanaka Hidetaka Okada Source Type: research