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Nutrition: Glucosamine
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Proteasomal degradation of O-GlcNAc transferase elevates hypoxia-induced vascular endothelial inflammatory response
Conclusions
26S proteasome-mediated OGT reduction contributed to hypoxia-induced vascular endothelial inflammatory response. Modulation of OGT may represent a new approach to treat diseases characterized by hypoxic inflammation.
Source: Cardiovascular Research - June 20, 2014 Category: Cardiology Authors: Liu, H., Wang, Z., Yu, S., Xu, J. Tags: Vascular biology Source Type: research