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Condition: Translocation
Nutrition: Ganoderma
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Khz-cp (crude polysaccharide extract obtained from the fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating P38 and NADPH oxidase-dependent generation of reactive oxygen species in SNU-1 cells
Conclusions:
In summary, these data indicate that Khz-cp preferentially induces apoptosis in cancer cells and that the signaling mechanisms involve an increase in [Ca2+]i, P38 activation, and ROS generation via NADPH oxidase and mitochondria.
Source: BMC Complementary and Alternative Medicine - July 10, 2014 Category: Complementary Medicine Authors: Tae KimJu KimZoo KimRen HuangYoung ChaeRen Wang Source Type: research
