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Rac1 GTPase is a critical factor in phagocytosis in the large yellow croaker Larimichthys crocea by interacting with tropomyosin
Publication date: Available online 11 May 2019Source: Fish & Shellfish ImmunologyAuthor(s): Fang Han, Wanbo Li, Xiande Liu, Dongling Zhang, Lanping Liu, Zhiyong WangAbstractThe Rho family GTPase Rac1 acts as a molecular switch for signal transduction to regulate various cellular functions. Here, a Rac1 homolog (LcRac1) was identified in large yellow croaker (Larimichthys crocea), one of the most economically important marine fishes. The LcRac1 protein was expressed in Escherichia coli and purified. Subsequently the specific antibody was raised using the purified fusion protein (GST-LcRac1). LcRac1 was ubiquitously expresse...
Source: Fish and Shellfish Immunology - May 16, 2019 Category: Biology Source Type: research
