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Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function.
In conclusion, to GBM therapy with a drug combination of TMZ and erastin may be beneficial. PMID: 25585997 [PubMed - as supplied by publisher]
Source: Oncology Reports - January 16, 2015 Category: Cancer & Oncology Tags: Oncol Rep Source Type: research