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Condition: Dermatitis
Infectious Disease: HIV AIDS
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Total 2 results found since Jan 2013.
Osthole relieves skin damage and inhibits chronic itch through modulation of Akt/ZO-3 pathway in atopic dermatitis
Eur J Pharmacol. 2023 Mar 13:175649. doi: 10.1016/j.ejphar.2023.175649. Online ahead of print.ABSTRACTAtopic dermatitis (AD) is the most prevalent chronic inflammatory skin condition and significantly reduces quality of life. Tight junction (TJ), which is located directly beneath the stratum corneum, maintains skin barrier function and aids in the identification of the cell's "territory". We evaluated seventeen TJ related genes to explore AD related alterations of TJ. Remarkably, we found that the expression of ZO-3, a gene that had not been linked to the development of TJ in AD, was significantly down-regulated in the ski...
Source: European Journal of Pharmacology - March 15, 2023 Category: Drugs & Pharmacology Authors: Xueqin Hu Yuan Zhou Jianxin Shi Mingxin Qi Xue Li Yan Yang Chan Zhu Changming Wang Zongxiang Tang Yuxiang Ma Guang Yu Source Type: research
