• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Dihydroartemisinin inhibits endothelial cell tube formation by suppression of the STAT3 signaling pathway
Publication date: Available online 24 December 2019Source: Life SciencesAuthor(s): Peng Gao, Li-li Wang, Jing Liu, Fengyun Dong, Wei Song, Lin Liao, Bei Wang, Wenqian Zhang, Xia Zhou, Qi Xie, Rong Sun, Ju LiuAbstractAimsEndothelial cell (EC) tube formation is crucial for tumor angiogenesis, which becomes a target for chemotherapy. The anti-malaria agent dihydroartemisinin (DHA) inhibited tumor growth and angiogenesis. The aim of this study was to investigate the effects of DHA on EC tube formation and the underlying mechanisms.Materials and methodsHuman umbilical vein endothelial cells (HUVECs) were cultured with different...
Source: Life Sciences - December 26, 2019 Category: Biology Source Type: research