• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

In  vitro inhibitory analysis of consensus siRNAs against NS3 gene of hepatitis C virus 1a genotype
Conclusions siRNAs directed against NS3 gene significantly decreased mRNA and protein expression in stable cell clones. Viral replication was also vividly decreased in serum infected Huh-7 cells. Stable Huh-7 cells expressing NS3 gene is helpful to develop anti-hepatitis C drug screening assays. siRNA therapeutic potential along with other anti-HCV agents can be considered against hepatitis C.
Source: Asian Pacific Journal of Tropical Medicine - August 18, 2017 Category: Tropical Medicine Source Type: research

In vitro inhibitory analysis of consensus siRNAs against NS3 gene of hepatitis C virus 1a genotype
Conclusions siRNAs directed against NS3 gene significantly decreased mRNA and protein expression in stable cell clones. Viral replication was also vividly decreased in serum infected Huh-7 cells. Stable Huh-7 cells expressing NS3 gene is helpful to develop anti-hepatitis C drug screening assays. siRNA therapeutic potential along with other anti-HCV agents can be considered against hepatitis C.
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2017 Category: Tropical Medicine Source Type: research