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Source: Renal Failure
Infectious Disease: Epidemics
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Total 1 results found since Jan 2013.
The inhibition of Nrf2 accelerates renal lipid deposition through suppressing the ACSL1 expression in obesity-related nephropathy.
Conclusions: The Nrf2 is inhibited in ORN, resulting more ROS production and oxidative stress. Increased oxidative stress will suppress the expression of ACSL1, which could increase the intracellular FFA and TG contents, ultimately leading to renal lipid deposition in renal tubulars and accelerating the development of ORN.
PMID: 31488013 [PubMed - in process]
Source: Renal Failure - September 7, 2019 Category: Urology & Nephrology Tags: Ren Fail Source Type: research
