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Source: European Review for Medical and Pharmacological Sciences
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Total 305 results found since Jan 2013.
TGF- β1 promotes proliferation and invasion of hepatocellular carcinoma cell line HepG2 by activating GLI-1 signaling.
CONCLUSIONS: TGF-β1 promotes HCC cell line HepG2 proliferation and invasion by activating GLI-1 signaling pathway.
PMID: 30536311 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - December 13, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
DUSP1 promotes senescence of retinoblastoma cell line SO-Rb5 cells by activating AKT signaling pathway.
CONCLUSIONS: DUSP1 facilitated human retinoblastoma SO-Rb5 cell senescence induced by AGII through inhibiting Akt signaling pathway.
PMID: 30536303 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - December 13, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
GAS5 promotes podocyte injury in sepsis by inhibiting PTEN expression.
CONCLUSIONS: GAS5 expression decreased in sepsis-induced podocyte injury, and GAS5 was involved in regulating sepsis-induced podocyte injury by reducing PTEN expression.
PMID: 30556845 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - December 18, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
lncRNA-RMRP promotes proliferation, migration and invasion of bladder cancer via miR-206.
CONCLUSIONS: According to the results, we found that lncRNA RMRP was closely related to the progression of bladder cancer, which could be a potential target for treating BC patients.
PMID: 30779067 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - February 21, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Astrocytes induce proliferation of oligodendrocyte progenitor cells via connexin 47-mediated activation of Chi3l1 expression.
CONCLUSIONS: Cx47/Chi3l1 plays an important role in the promotion of OPCs proliferation by ASTs. ASTs can promote the expression of Chi3l1 via Cx47 in OPCs, and then activate the expression of cyclin D1 and regulate the cell cycle of OPCs, thereby promoting cell proliferation. This study provides a new target for the treatment of neurodegenerative diseases.
PMID: 31002152 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - April 21, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
LncRNA PVT1 knockdown affects proliferation and apoptosis of uveal melanoma cells by inhibiting EZH2.
CONCLUSIONS: LncRNA PVT1 knockdown in UM cells can repress the proliferation of UM cells and promote their apoptosis by regulating EZH2 expression.
PMID: 31002139 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - April 21, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
MicroRNA-448 inhibits the regeneration of spinal cord injury through PI3K/AKT/Bcl-2 axis.
CONCLUSIONS: MicroRNA-448 is upregulated after SCI, which may be involved in the regenerative process of spinal motor nerves by regulating PI3K/AKT/Bcl-2 axis.
PMID: 31002121 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - April 21, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
KLF5 silence attenuates proliferation and epithelial-mesenchymal transition induction in Hep-2 cells through NF- κB signaling pathway.
CONCLUSIONS: These results revealed that silencing KLF5 expression reduced the proliferation, migration and invasion and EMT abilities by inhibiting the NF-κB pathway in Hep-2 cells. Our results suggest that KLF5 may be a potential therapeutic target in laryngeal carcinoma.
PMID: 31115014 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - May 24, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
LncRNA NKILA inhibits invasion and migration of osteosarcoma cells via NF- κB/Snail signaling pathway.
CONCLUSIONS: NKILA was lowly expressed in osteosarcoma tissues. In addition, high expression of NKILA could suppress the migration and invasion of osteosarcoma cells by inhibiting the NF-κB/Snail signaling pathway.
PMID: 31173281 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - June 9, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
The modulation of endometriosis by lncRNA MALAT1 via NF- κB/iNOS.
CONCLUSIONS: LncRNA MALAT1 can facilitate endometrial cell apoptosis and modulate MMP-9 expression via NF-κB/iNOS pathway, thus, mediating Ems pathogenesis.
PMID: 31173276 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - June 9, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
LINC00968 accelerates the progression of epithelial ovarian cancer via mediating the cell cycle progression.
CONCLUSIONS: LINC00968 expression is markedly upregulated in EOC. Meanwhile, it arrests the cell cycle in the G1 phase by inhibiting the ERK and AKT pathways, thus accelerating EOC progression.
PMID: 31210289 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - June 20, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Effect of NLK on the proliferation and invasion of laryngeal carcinoma cells by regulating CDCP1.
CONCLUSIONS: NLK is expressed in tumor tissues of patients with laryngeal cancer. The down-regulation of NLK expression may play a role in the proliferation, apoptosis, and invasion of laryngeal carcinoma cells and it is possible by regulating MMP-9 and CDCP1 expression.
PMID: 31364124 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - August 2, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
PLCE1 inhibits apoptosis of non-small cell lung cancer via promoting PTEN methylation.
CONCLUSIONS: PLCE1 inhibits cell apoptosis of NSCLC by promoting PTEN methylation.
PMID: 31364122 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - August 2, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Downregulated LINC00460 inhibits cell proliferation and promotes cell apoptosis in prostate cancer.
CONCLUSIONS: LINC00460 could regulate cell proliferation and cell apoptosis, which might be a novel marker in prostate cancer.
PMID: 31364108 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - August 2, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.
CONCLUSIONS: Our work may help understand the roles of Kif4 in monocyte/macrophage cells and would give useful information on basic research and the function of monocyte/macrophage cells.
PMID: 31486502 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - September 7, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
