Filtered By:
Source: Experimental and Therapeutic Medicine
Drug: Docetaxel
This page shows you your search results in order of date.
Order by Relevance | Date
Total 2 results found since Jan 2013.
ChaC glutathione specific γ-glutamylcyclotransferase 1 inhibits cell viability and increases the sensitivity of prostate cancer cells to docetaxel by inducing endoplasmic reticulum stress and ferroptosis
Exp Ther Med. 2021 Sep;22(3):997. doi: 10.3892/etm.2021.10429. Epub 2021 Jul 15.ABSTRACTThe present study aimed to determine the effects and mechanism of ChaC glutathione specific γ-glutamylcyclotransferase 1 (CHAC1) on cell viability and the sensitivity of prostate cancer cells to docetaxel. Compared with non-tumor human prostate epithelial RWPE-1 cells, the mRNA and protein levels of CHAC1 significantly decreased in two prostate cancer cell lines, DU145 and 22RV1, as measured by quantitative polymerase chain reaction and western blot analysis (P<0.05). The cell viability and glutathione (GSH) levels were significantl...
Source: Experimental and Therapeutic Medicine - August 4, 2021 Category: General Medicine Authors: Saifei He Miao Zhang Ying Ye Juhua Zhuang Xing Ma Yanan Song Wei Xia Source Type: research
