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Curcumin increases cholesterol efflux via heme oxygenase ‑1‑mediated ABCA1 and SR‑BI expression in macrophages.
Curcumin increases cholesterol efflux via heme oxygenase‑1‑mediated ABCA1 and SR‑BI expression in macrophages. Mol Med Rep. 2018 Feb 08;: Authors: Zhong Y, Feng J, Fan Z, Li J Abstract Curcumin, which is an extract from a traditional Chinese medicine, has previously been demonstrated to exhibit an anti‑atherosclerotic effect, which is closely associated with an increase in cholesterol efflux. However, it is unclear as to whether the increased effect is mediated by heme oxygenase (HO)‑1. Macrophages were treated with different concentrations of curcumin, HO‑1 inhibitor and small interfering ...
Source: Molecular Medicine Reports - February 14, 2018 Category: Molecular Biology Tags: Mol Med Rep Source Type: research