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Source: Oncology Letters
Condition: von Willebrand Disease

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Total 3 results found since Jan 2013.

Connexin 43 overexpression induces lung cancer angiogenesis < em > in vitro < /em > following phosphorylation at Ser279 in its C-terminus
Oncol Lett. 2022 Jul 5;24(3):293. doi: 10.3892/ol.2022.13413. eCollection 2022 Sep.ABSTRACTBlocking angiogenesis can inhibit tumor growth and metastasis. However, the mechanism underlying regulation of lung cancer angiogenesis remains unclear. The gap junction protein connexin 43 (Cx43) is implicated in angiogenesis. The aim of the present study was to determine the role of Cx43 in angiogenesis in vitro and its signaling pathways. Human pulmonary microvascular endothelial cells were transfected with Cx43-targeting siRNA or Cx43-overexpressing recombinant plasmid vector. Reverse transcription-quantitative polymerase chain r...
Source: Oncology Letters - August 11, 2022 Category: Cancer & Oncology Authors: Zizi Zhou Wenxiang Chai Yi Liu Yao Liu Huiyu Pan Qiang Wu Xiaoming Zhang Source Type: research