• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Nanoscale microenvironment engineering based on layer-by-layer self-assembly to regulate hair follicle stem cell fate for regenerative medicine
Conclusion: This study provides novel methods for the construction of stem cell microenvironments and experimental models of HF regeneration for the treatment of hair loss.
Source: Theranostics - October 3, 2020 Category: Molecular Biology Authors: Peng Chen, Yong Miao, Feifei Zhang, Junfei Huang, Yuxin Chen, Zhexiang Fan, Lunan Yang, Jin Wang, Zhiqi Hu Tags: Research Paper Source Type: research

FGF9 induces functional differentiation to Schwann cells from human adipose derived stem cells
Conclusions: Our data therefore demonstrate the importance of FGF9 in the determination of SC fate via the FGF9-FGFR2-Akt pathway and reveal the therapeutic benefit of FGF9-NLCs.
Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Chia-Wei Huang, Shih-Yu Lu, Tzu-Chieh Huang, Bu-Miim Huang, H. Sunny Sun, Shang-Hsun Yang, Jih-Ing Chuang, Yuan-Yu Hsueh, Yi-Ting Wu, Chia-Ching Wu Tags: Research Paper Source Type: research

Dysbiosis of intestinal microbiota mediates tubulointerstitial injury in diabetic nephropathy via the disruption of cholesterol homeostasis
Conclusion: Our studies for the first time demonstrated that the acetate produced from gut microbiota mediated the dysregulation of cholesterol homeostasis through the activation of GPR43, thereby contributing to the tubulointerstitial injury of DN, suggesting that gut microbiota reprogramming might be a new strategy for DN prevention and therapy.
Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Ze Bo Hu, Jian Lu, Pei Pei Chen, Chen Chen Lu, Jia Xiu Zhang, Xue Qi Li, Ben Yin Yuan, Si Jia Huang, Xiong Zhong Ruan, Bi Cheng Liu, Kun Ling Ma Tags: Research Paper Source Type: research

Photoluminescent Mesoporous Silicon Nanoparticles with siCCR2 Improve the Effects of Mesenchymal Stromal Cell Transplantation after Acute Myocardial Infarction
Conclusions: PMSNs-siCCR2-mediated CCR2 gene silencing in Ly6Chigh monocytes improved the effectiveness of MSC transplantation and selectively ameliorated myocardial remodeling after AMI. These results suggest that PMSNs-siCCR2 could potentially be used to develop an anti-inflammatory therapy for post-AMI MSC transplantation.
Source: Theranostics - September 18, 2015 Category: Molecular Biology Authors: Wenbin Lu, ZhuoYing Xie, Yong Tang, Ling Bai, Yuyu Yao, Cong Fu, Genshan Ma Tags: Research Paper Source Type: research