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Inhibition of SGK1 confers vulnerability to redox dysregulation in cervical cancer
Publication date: Available online 20 May 2019Source: Redox BiologyAuthor(s): Min Wang, Yijue Xue, Lanlin Shen, Pan Qin, Xiaolin Sang, Zhiwei Tao, Jingyan Yi, Jia Wang, Pixu Liu, Hailing ChengAbstractCervical cancer has poor prognosis and patients are often diagnosed at advanced stages of the disease with limited treatment options. There is thus an urgent need for the discovery of new therapeutic strategies in cervical cancer. The activation of SGK1 has been linked to the development of various cancer types but little is known about the role of SGK1 in cervical cancer and its potential as a therapeutic target. Here we repo...
Source: Redox Biology - May 22, 2019 Category: Biology Source Type: research