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Source: Pathology Research and Practice
Therapy: Palliative
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Decreased IL-6 induces sensitivity of hepatocellular carcinoma cells to sorafenib
Publication date: Available online 25 July 2019Source: Pathology - Research and PracticeAuthor(s): Jing Yang, Jiali Wang, Jialin LuoAbstractSorafenib has been recommended as a new palliative therapy for advanced hepatocellular carcinoma (HCC). However, the sensitivity of HCC cells to sorafenib is declined along with the extension of medication time, and the clinical outcome varies with patients receiving sorafenib therapy. Therefore, in the present study, we attempted to investigate the effect and mechanisms of IL-6 on sensitivity of HCC cells to sorafenib regarding the cell proliferation and apoptosis. Tissues from patien...
Source: Pathology Research and Practice - July 25, 2019 Category: Pathology Source Type: research
