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Source: Molecular and Cellular Endocrinology

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Total 76 results found since Jan 2013.

ALK4-SMAD3/4 mediates the effects of activin A on the upregulation of PAI-1 in human granulosa lutein cells
Publication date: Available online 23 January 2020Source: Molecular and Cellular EndocrinologyAuthor(s): Beili Chen, Hsun-Ming Chang, Zhiguo Zhang, Yunxia Cao, Peter C.K. LeungAbstractIn the mammalian ovary, the proteolysis of the extracellular matrix is dynamically regulated by plasminogen activator and plasminogen activator inhibitor (PAI), and it is a critical event that influences various physiological and pathological processes. Activin A is a member of the transforming growth factor-β superfamily and is expressed at a high level in human luteal cells that play an essential role in the regulation of the luteal functi...
Source: Molecular and Cellular Endocrinology - January 24, 2020 Category: Endocrinology Source Type: research