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Source: Molecular and Cellular Endocrinology
Condition: Cardiomyopathy
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Total 1 results found since Jan 2013.
Inhibition of prolyl hydroxylase 3 ameliorates cardiac dysfunction in diabetic cardiomyopathy
Publication date: 5 March 2015 Source:Molecular and Cellular Endocrinology, Volume 403 Author(s): Yanfei Xia , Luwei Gong , Hui Liu , Beibei Luo , Bo Li , Rui Li , Beibei Li , Mei Lv , Jinyu Pan , Fengshuang An Prolyl hydroxylase 3 (PHD3) is a member of the prolyl hydroxylases (PHDs) family and is induced by hypoxia. It plays a critical role in regulating the abundance of hypoxia-inducible factor (HIF). Its expression is increased in diabetic rat hearts; however, its role remains unclear. We investigated the potential role and mechanism of action of PHD3 in the setting of diabetes-induced myocardial dysfunction in rats. ...
Source: Molecular and Cellular Endocrinology - January 27, 2015 Category: Endocrinology Source Type: research
