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Source: Biochimica et Biophysica Acta (BBA) Molecular Cell Research
Drug: Diltiazem
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Homer proteins mediate the interaction between STIM1 and Cav1.2 channels
Publication date: Available online 21 February 2015 Source:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Author(s): Natalia Dionisio , Tarik Smani , Geoffrey E. Woodard , Antonio Castellano , Gines M. Salido , Juan A. Rosado STIM1 is an ubiquitous Ca2+ sensor of the intracellular, agonist-sensitive, Ca2+ stores that communicates the filling state of the Ca2+ compartments to plasma membrane store-operated Ca2+ (SOC) channels. STIM1 has been presented as a point of convergence between store-operated and voltage-operated Ca2+ influx, both inducing activation of SOC channels while suppressing Cav1.2 channels....
Source: Biochimica et Biophysica Acta (BBA) Molecular Cell Research - February 22, 2015 Category: Molecular Biology Source Type: research
