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Nutrition: Vitamins
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Abstract 191: Transcriptional Regulation of Renin by Nuclear Receptors Co-regulated With Renin Poster Session I
Expression of the renin gene is required to maintain normal morphological and physiological identity of renal juxtaglomerular (JG) cells, yet the mechanisms regulating renin gene transcription remain elusive. We re-examined data from Brunskill et. al (JASN 22:2213, 2011), investigating genome-wide gene expression in JG and other renal cell types. Based on our previous data implicating nuclear receptors (RAR, RXR, VDR, PPARG, Nr2f2 and Nr2f6) in the regulation of mouse and human renin gene expression, we focused our analysis on the expression of genes encoding the 48 nuclear hormone receptors and their co-regulation with re...
Source: Hypertension - October 30, 2013 Category: Cardiology Authors: Lu, K.-T., Weatherford, E. T., Ketsawatsomkron, P., Grobe, J. L., Sigmund, C. D. Tags: Poster Session I Source Type: research
