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Value of long non-coding RNA Rpph1 in esophageal cancer and its effect on cancer cell sensitivity to radiotherapy.
CONCLUSION: Rpph1 is highly expressed in esophageal cancer. Silencing Rpph1 expression can promote cell apoptosis, inhibit cell proliferation and migration, and increase radio-sensitivity. PMID: 32351293 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - April 20, 2020 Category: Gastroenterology Authors: Li ZY, Li HF, Zhang YY, Zhang XL, Wang B, Liu JT Tags: World J Gastroenterol Source Type: research

Role of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations.
CONCLUSION: AXL is influenced by p53 status and could cause the emergence of aggressive clones after exposure to chemotherapy. These findings could have applications in cancer management. PMID: 28596680 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - May 21, 2017 Category: Gastroenterology Authors: Abdel-Rahman WM, Al-Khayyal NA, Nair VA, Aravind SR, Saber-Ayad M Tags: World J Gastroenterol Source Type: research

Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-κB signaling in colorectal cancer cells.
CONCLUSION: ILK overexpression improved the proliferation, metastasis, and invasion ability of SW480 cells, and this effect may be mediated by the NF-κB signaling pathway. PMID: 27099440 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - April 20, 2016 Category: Gastroenterology Authors: Shen H, Ma JL, Zhang Y, Deng GL, Qu YL, Wu XL, He JX, Zhang S, Zeng S Tags: World J Gastroenterol Source Type: research

Linc00675 is a novel marker of short survival and recurrence in patients with pancreatic ductal adenocarcinoma.
CONCLUSION: Linc00675 may function as an oncogene during PDAC development, and its expression is an independent predictor of unfavorable prognosis in patients with PDAC. PMID: 26309360 [PubMed - as supplied by publisher]
Source: World Journal of Gastroenterology : WJG - August 21, 2015 Category: Gastroenterology Authors: Li DD, Fu ZQ, Lin Q, Zhou Y, Zhou QB, Li ZH, Tan LP, Chen RF, Liu YM Tags: World J Gastroenterol Source Type: research

Interference of suppressor of cytokine signaling 3 promotes epithelial-mesenchymal transition in MHCC97H cells.
CONCLUSION: SOCS3 silencing is able to promote EMT in MHCC97H cells via changing the phenotypic characteristics and modulating the characteristic markers. PMID: 23430705 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - February 14, 2013 Category: Gastroenterology Authors: Ji YY, Wang ZD, Li ZF, Li K Tags: World J Gastroenterol Source Type: research